Principles for next generation anti-cancer immunotherapy
- ISBN/EAN
- 9788855322317
- Editore
- Minerva Medica
- Formato
- Libro
- Anno
- 2024
- Pagine
- 360
Disponibile
lmmunotherapy is considered the fourth pillar in the treatment against cancer, together with surgery, chemotherapy, and radiotherapy. Since the approval of ipilimumab in 2011 for metastatic melanoma, many immunotherapy treatments have been approved. They have led to a clear increase in survival of patients with several cancers, including lung, kidney, head and neck, urothelial, bladder, colon with microsatellite instability, breast, and Hodgkin lymphoma. The clinical success of immune checkpoint blockade with anti-cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) and anti-programmed death (PD)-1/programmed death ligand 1 (PD-L 1) inhibitors has encouraged the development of other immunotherapies. The new frontiers of immunotherapy are combination and sequence therapies, with the aim of reducing resistance, increasing responses, and decreasing toxicity. Furthermore, several innovative approaches are under evaluation: immune targets, adoptive cell transfer, and vaccines, all of which could increase the efficacy of such a strategy. In this book we discuss the most important advances in this field.
Maggiori Informazioni
| Autore | Ascierto Paolo Antonio |
|---|---|
| Editore | Minerva Medica |
| Anno | 2024 |
| Tipologia | Libro |
| Lingua | Inglese |
| Indice | Fundamentals of tumour immunology Giuseppe V. Masucci, Lisa Villabona Immune oncology and immune responsiveness Ena Wang, Domenico Mallardo, Francesco M. Marincola The role of the tumor microenvironment Assia Hijazi, Jérôme Galon Biomarkers in immunotherapy Giuseppe Palmieri, Vincenza Caridi, Nicola Normanno Mechanisms of resistance to immunotherapies Mariaelena Capone, Gabriele Madonna Immunotherapy in metastatic melanoma Claudia Trojaniello, Francesca Sparano, Paolo Antonio Ascierto Immunotherapy and lung cancer Alessia Spagnuolo, Cesare Gridelli Immunotherapy in breast cancer Liliana Ascione, Celeste Santoro, Dario Trapani, Giuseppe Curigliano Immunotherapy in gastrointestinal cancer Antonio Avallone, Alfredo Budillon Immunotherapy in non-melanoma skin cancers Lucia Festino, Margaret Ottaviano Immunotherapy in urothelial cancers and renal cell carcinoma Sergio Bracarda, Claudia Mosillo, Annalisa Guida Immunotherapy in head and neck cancer Paolo Bossi, Maria Grazia Ghi Combination strategies Omid Hamid, Francesca Sparano, Paolo Antonio Ascierto Adoptive cellular therapy (ACT) in melanoma Elham Nasrollahi, Diwakar Davar Management of immune checkpoint inhibitor side effects Benjamin Switzer, Douglas B. Johnson, Igor Puzanov The role of gut microbiota in cancer immunotherapy efficacy Serena Galiè, Carlotta Catozzi, Luigi Nezi |
| Larghezza | 0 |
| Stato editoriale | In Commercio |