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Magnetic Resonance Techniques In Clinical Trials In Multiple Sclerosis

ISBN/EAN
9788847000414
Editore
Springer Verlag
Collana
Topics in neuroscience
Formato
Brossura
Anno
1999
Pagine
192

Disponibile

150,75 €
The therapeutic era for MS has begun, and many new, potentially effective treatments are now available. MRI offers a range of techniques which are more reliable and sensitive than any other available approach in detecting brain and spinal cord abnormalities, monitoring their evolution, and providing in vivo information about heterogenous pathological substrates of the MS lesions. Readers will find this volume a valuable summary of the state-of- the art, as well as a useful reference text from which to plan future clinical trials in MS.

Maggiori Informazioni

Autore Filippi M.; Grossman R.I.; Comi G.
Editore Springer Verlag
Anno 1999
Tipologia Libro
Collana Topics in neuroscience
Num. Collana 0
Lingua Inglese
Indice Introduction 1 Clinical and Paraclinical Outcomes for Treatment Trials in Multiple Sclerosis 3 The Use of Magnetic Resonance Imaging to Select Patients for Multiple Sclerosis Clinical Trials 21 The Application of Magnetic Resonance Imaging to Phase II Trials in Multiple Sclerosis 37 Magnetic Resonance Imaging Techniques to Monitor Phase III Treatment Trials 49 New Strategies to Increase Magnetic Resonance Imaging Sensitivity in Detecting Individual Multiple Sclerosis Lesions and Short-term Disease Activity: Perspectives for Future Clinical Trials 74 Problems with Conventional Magnetic Resonance Imaging and New Strategies to Improve the Utility of MRI in Future Clinical Trials 85 Review of the Results of Previous Phase II, Magnetic Resonance Imaging-monitored Clinical Trials 106 Magnetic Resonance Imaging Techniques in Phase III Clinical Trials in Multiple Sclerosis 134 Standardisation, Optimisation and Organisation of Magnetic Resonance Imaging for Monitoring Clinical Trials 145 Statistical Approaches to the Use of Magnetic Resonance Imaging Data for Clinical Trials 168 Subject Index