Harrison's Principles of Internal Medicine, 19/ed. Voll. 1/2 + DVD Rom [Kasper; Fauci; Hauser - McGraw-Hill Companies]

Capturing the countless advances and developments across the full span of medicine, the new nineteenth edition of Harrison’s Principles of Internal Medicine is completely revised providing an update of essential content related to disease pathogenesis, clinical trials, current diagnostics methods, evidence-based practice guidelines, and established and newly approved treatment methods. Presented in two practical volumes, Harrison’s new functional format is structured to allow readers to easily access information relevant to their specific needs. Volume 1: Basic Principles and Cardinal Manifestations of Diseases covers essential foundational-level material underlying better patient care and assessment of signs and symptoms. Volume 2: Disease Pathogenesis and Treatment is dedicated to specific disease and the best evidence-based approaches to their management. The nineteenth edition features dynamic new chapters on established and emerging issues in clinical medicine and medical science, such as Men’s Health, Lung Abscess, Fatigue, and more. Also included are supplemental resources that reflect and assist modern medical practice: 1,000 full-color photographs; hundreds of state-of-the-art radiographs; more state-of-the-art illustrations; the renowned Harrison’s patient-care algorithms, essential summary tables, and practical demonstrative videos. Harrison’s editors provide critical updates to landmark chapters on key issues, such as HIV and AIDS, Cancer Biology, Introduction to the Immune System, Multiple Sclerosis, Kidney Dialysis, and Chronic Hepatitis, Coronary Artery Disease, Ebola Virus Disease, Multiple Sclerosis, Diabetes, Hypertension, Inflammatory Bowel Disease, Lipoprotein Disorders, and many more. The Harrison’s DVD has been expanded to include 137 e-chapters. They provide deeper insight into essential medical education and clinical medical topics, in addition to offering these other outstanding features: More than 153 videos with step-by-step procedures performed at the bedside Hundreds of additional images from imaging and clinical pathology New videos covering important topics, such as sleep disorders, tissue engineering, and noninvasive cardiac imaging 137 additional chapters and more than 500 images make the companion DVD an essential part of every physician's education, practice, and lifelong learning. This companion DVD is an essential part of every physician’s education, practice, and lifelong learning. The DVD also allows you to preview two indispensable online medical resources FREE AccessMedicine, featuring Harrison’s Online, and ClinicalAccess Essentials — targeted answers to 120,000 clinical questions. ---------------------------------------------------------------------------------------------------------------------------------------------------------- Supporting the renowned coverage are supplemental resources that reflect and assist modern medical practice: more than 1,000 full-color photographs to aid visual recognition skills, hundreds of state-of-the- art radiographs, from plain film to 3D CT to PET Scans; beautiful illustrations that bring applied anatomy and processes to life; the renowned Harrison’s patient-care algorithms, essential summary tables, and practical demonstrative videos. In addition, the book’s several digital atlases highlight noninvasive imaging, percutaneous revascularization, gastrointestinal endoscopy, diagnosis and management of vasculitis, and numerous other issues commonly encountered in clinical practice. Volume 1: Basic Principles and Cardinal Manifestations of Disease covers essential foundational- level material on the basic principles underlying optimal patient care and assessment of signs and symptoms.  The core principles of internal medicine in one convenient volume, including the famous “The Practice of Medicine” chapter  Content on Cardinal Manifestations of Diseases offers unmatched guidance on the physiological basis of presenting complaints, making it the perfect resource for establishing the scientific and clinical basis of differential diagnosis  Seamlessly integrates basic and clinical science, and delivers complete coverage of physiology, pathophysiology, pharmacology, and therapeutics  Just the right balance of detail with quick reference features such as algorithms, highlighted text for quick references, outstanding images and illustrations, and summary tables and lists Volume 2: Disease Pathogenesis and Treatment devoted to specific diseases and the best evidence- based approaches to their management.  A complete and current review of hundreds of specific diseases, accompanied by data-driven approaches to their management  Provides high-yield guidance on the pathogenesis and treatment of disease entities, by system  Covers the full spectrum of conditions and disorders, from cancers and infectious diseases to cardiovascular and respiratory disorders  Features current clinical perspectives on pathophysiology, clinical trial results, evidence-based practice guidelines, diagnostic methods, and established and new treatment modalities  Offers clarity on important clinical issues and decisions such as the use of aspirin therapy in ischemic heart disease, the benefits and risks of tight blood pressure control, optimal strategies for anti-coagulation, genetics and genomics in the management of neuromuscular disorders, current management of liprotein disorders, effective use of targeted and immune-based cancer therapies, new biomarkers for assessing common clinical conditions, and more.  A thorough and handy resource for the current practice of clinical medicine, with hundreds of algorithms, radiographs, and illustrations supplementing the text, striking the perfect balance between detail and quick access Multimedia Companion DVD  Contains 136 e-chapters which are drawn from the parent text and provide deeper insight into essential medical education and clinical medicine topics  Features more than 140 videos with precise, step-by-step demonstrations of procedures performed at the bedside  Provides access to hundreds of additional images of from imaging and clinical pathology  New videos cover such important topics including sleep disorders, tissue engineering, noninvasive cardiac imaging, the examination of the comatose patient, and myasthenia and other diseases of the neuromuscular junction Clinical Algorithms Harrison’s is renowned for its collection of clinical algorithms that speed bedside decision making. They offer expert and evidence-based guidance on the diagnosis and treatment of common and challenging conditions. Important Chapter Updates With each new edition, the Harrison’s editors provide critical updates to landmark chapters on key issues in medical science and clinical medicine. The Nineteenth Edition is highlighted by these important chapter updates:  HIV and AIDS presents the latest understanding of the biology of acquired immune deficiency and a complete update of therapeutic options in the long-term management of HIV infection and AIDS.  Cancer Biology includes major updates on the rapidly progressing knowledge base of cancer mechanisms, and includes significant new content on the metabolic behavior of cancerous cells.  Introduction to the Immune System is an effective primer that provides a complete framework for all clinicians to apply basic science to everyday patient care.  Multiple Sclerosis provides a new understanding of epidemiology and new options for ongoing therapeutics.  Non-STEMI, the acclaimed chapter by Cannon and Braunwald, has been exhaustively updated, and provides the current state of knowledge of mechanisms and management.  New Imaging Techniques in Cardiovascular Diseases reflects the rapid progress of optical coherence tomography and intravascular ultrasound, whose clinical use is now unquestioned.  Deep Vein Thrombosis and Pulmonary Embolism delivers a completely updated review of the pathophysiology and epidemiology of DVT and PE, risk stratification in pulmonary embolism, optimal strategies for anticoagulation, use of novel anticoagulant agents, and updated information on pharmacomechanical catheter-directed therapy of venous thromboembolism.  Kidney Dialysis features updated evidence concerning the optimal weekly frequency of dialysis, and a completely updated review of major trials addressing long-term cardiovascular and other outcomes in End-Stage Renal Disease.  Chronic Hepatitis delivers important updates on the use of new therapeutic agents for the management of Hepatitis C infection.  Lipoprotein Disorders has been completely updated to reflect new classification schemes. New Chapters The Nineteenth Edition of Harrison’s Principles of Internal Medicine includes dynamic new chapters on established and emerging issues in clinical medicine and medical science, including:  Men’s Health  Fatigue  Chronic Myeloid Leukemia  Microbial Genomics and Infectious Diseases  The Influence of Climate Change on Infectious Disease  Infections in Veterans Returning from Foreign Wars  Lung Abscess  Introduction to the Helminthic Infection  Polyglandular Failure Syndromes Author Biographies Dennis L. Kasper, MD (Boston, MA) is Professor of Medicine at Harvard Medical School and a leading researcher of the health and disease implications related to the human microbiome. Anthony S. Fauci, MD (Bethesda, MD) is Director of the National Institutes for Allergy and Infectious Diseases, and recipient of the 2007 Lasker Prize for Medicine along with many other awards too numerous to mention. He is the chief federal official responsible for policy in AIDS and HIV research and public health, as well as bioterrorism response. Stephen L. Hauser MD (San Francisco, CA) is Chair of Neurology at UCSF and a neuroimmunologist whose research has advanced our understanding of the genetic basis, immune mechanisms, and treatment of multiple sclerosis. Dan L. Longo, MD (Boston, MA) is a long-time Harrison's editor, and is Professor of Medicine at Harvard Medical School and a Senior Physician at Brigham and Women’s Hospital. Dr. Longo is a cancer specialist. J. Larry Jameson, MD, PhD (Philadelphia, PA) is Executive Vice President of the University of Pennsylvania Health System and Dean of the Perelman School of Medicine at the University of Pennsylvania. Joseph Loscalzo MD, PhD (Boston, MA) is Hersey Professor of the Theory and Practice of Medicine at Harvard Medical School. He is editor-in-chief of the leading journal in cardiology, Circulation.